Fluoro calcium phosphosilicate Nanoparticles/Nanopowder (CaO:SiO2:P2O5:MgO:K2O:Na2O:CaF2, <100nm, Purity 99.5%)
₹1475.00
Fluoro Calcium Phosphosilicate Nanoparticles / Nanopowder (CaO:SiO₂:P₂O₅:MgO:K₂O:Na₂O:CaF₂, <100 nm, Purity 99.5%)
⚙️ Technical Specifications
Property | Specification |
|---|---|
Product Name | Fluoro Calcium Phosphosilicate Nanoparticles / Nanopowder |
Chemical Composition | CaO:SiO₂:P₂O₅:MgO:K₂O:Na₂O:CaF₂ |
Purity | ≥ 99.5% |
Particle Size (APS) | <100 nm |
Appearance | White to off-white amorphous powder |
Structure | Amorphous / partially crystalline |
Density | ~2.7 g/cm³ |
Specific Surface Area (BET) | 50–180 m²/g |
pH (in suspension) | Neutral (6.8–7.5) |
Solubility | Insoluble in water; reacts with body fluids |
Ionic Components Released | Ca²⁺, Si⁴⁺, PO₄³⁻, F⁻, Na⁺, K⁺, Mg²⁺ |
CAS Number | N/A (multi-component material) |
🌟 Key Features
High-purity (<100 nm) bioactive glass–ceramic nanoparticles doped with fluoride (CaF₂)
Combines bioactivity, remineralization ability, and fluoride release
Forms fluorapatite (FAp) and hydroxyapatite (HAp) layers in physiological fluids
Excellent biocompatibility, bioactivity, and ion-exchange reactivity
Ideal for bone, dental, and regenerative biomaterial applications
Enhanced mechanical stability and chemical durability due to CaF₂ incorporation
🔬 Applications (in Detail)
1. Dental Remineralization & Enamel Repair
Promotes tooth enamel remineralization and dentin tubule occlusion.
Releases Ca²⁺, PO₄³⁻, and F⁻ ions to form fluorapatite (Ca₁₀(PO₄)₆F₂), a stable, acid-resistant layer.
Used in toothpastes, varnishes, dental composites, and remineralizing gels.
2. Bone Regeneration & Tissue Engineering
Supports osteoblast proliferation and new bone formation.
Forms a bioactive layer of fluorapatite/hydroxyapatite on bone surfaces.
Used in scaffolds, bone cements, and implants for improved osseointegration and mechanical strength.
3. Bioactive Coatings for Implants
Fluoro calcium phosphosilicate coatings enhance biointegration and bacterial resistance.
Fluoride doping improves chemical durability and bonding strength with metallic implants (e.g., Ti, CoCr).
4. Drug Delivery & Therapeutic Carriers
Acts as a biodegradable and ion-releasing carrier for antibiotics, growth factors, or calcium fluoride nanoparticles.
Provides controlled ion release to support bone and dental healing processes.
5. Wound Healing & Soft Tissue Regeneration
Stimulates angiogenesis and cell proliferation.
Fluoride ions help enhance collagen cross-linking and cell adhesion.
Applied in bioactive dressings, gels, and tissue scaffolds.
6. Antibacterial & Anti-Caries Applications
Released fluoride ions (F⁻) inhibit bacterial metabolism and plaque formation.
Used in dental sealants, restorative materials, and orthodontic adhesives for long-term protection.
7. Composite & Hybrid Materials
Incorporated into hydroxyapatite, chitosan, PCL, or PLA composites to enhance bioactivity, mechanical stability, and ion delivery.
Suitable for 3D-printed scaffolds, bioactive fillers, and nanocomposite coatings.
⚠️ Handling & Storage
Store in a tightly sealed container in a cool, dry environment.
Avoid exposure to moisture and CO₂ to maintain reactivity.
Handle using gloves, mask, and safety goggles to prevent nanoparticle inhalation.
Sterilize before biomedical use (e.g., autoclaving, UV, or ethanol treatment).