Bioactive Glass Nanoparticles/Nanopowder (CaO:SiO2:P2O5:MgO:K2O:Na2O, <100nm, Purity 99.5%)

₹1475.00

Bioactive Glass Nanoparticles / Nanopowder (CaO:SiO₂:P₂O₅:MgO:K₂O:Na₂O, <100 nm, Purity 99.5%)


⚙️ Technical Specifications

Property

Specification

Product Name

Bioactive Glass Nanoparticles / Nanopowder

Chemical Composition

CaO:SiO₂:P₂O₅:MgO:K₂O:Na₂O (typical molar ratio similar to 45S5 or modified bioglass)

Purity

≥ 99.5%

Particle Size (APS)

<100 nm

Appearance

White to off-white amorphous fine powder

Structure

Amorphous / partially crystalline

Density

~2.6 g/cm³

Specific Surface Area (BET)

50–200 m²/g (high surface reactivity)

Solubility

Insoluble in water; reacts with physiological fluids

pH (in suspension)

7–8 (neutral)

Porosity

Mesoporous (optional depending on synthesis)

CAS Number

N/A (composite material)


🌟 Key Features

  • High-purity (<100 nm) bioactive glass nanoparticles with excellent biocompatibility

  • Exhibits osteoconductive and osteostimulative behavior

  • Capable of forming a hydroxyapatite (HAp) layer on contact with body fluids

  • High surface area and reactivity for biological integration

  • Customizable composition (CaO–SiO₂–P₂O₅–MgO–K₂O–Na₂O) for tailored bioactivity

  • Non-toxic, bioresorbable, and environmentally stable

  • Suitable for biomedical, dental, and tissue engineering applications


🔬 Applications (in Detail)

1. Bone Regeneration & Tissue Engineering

  • Promotes new bone formation through release of Ca²⁺, Si⁴⁺, and PO₄³⁻ ions.

  • Used in scaffold coatings, bone graft substitutes, and 3D-printed implants.

  • Supports cell adhesion, proliferation, and differentiation of osteoblasts.


2. Dental Applications

  • Used in tooth remineralization, dentin hypersensitivity reduction, and enamel repair.

  • Forms a hydroxycarbonate apatite (HCA) layer on tooth surfaces, mimicking natural enamel.

  • Incorporated in toothpastes, dental fillers, and restorative materials.


3. Drug Delivery Systems

  • Acts as a biodegradable carrier for controlled release of drugs, antibiotics, or growth factors.

  • Mesoporous surface allows high drug loading and sustained release.

  • Ideal for targeted local therapy in bone and tissue repair.


4. Coatings for Implants & Medical Devices

  • Applied as a bioactive coating on metallic or polymeric implants.

  • Improves osseointegration and biocompatibility of orthopedic and dental implants.

  • Reduces risk of implant rejection and infection.


5. Wound Healing & Soft Tissue Repair

  • Enhances angiogenesis (blood vessel formation) and cell regeneration.

  • Used in bioactive dressings and tissue scaffolds.

  • Stimulates collagen synthesis and accelerates healing.


6. Bioceramic Composites

  • Added to hydroxyapatite, chitosan, PLA, or PCL matrices to improve mechanical strength, bioactivity, and ion release.

  • Used in 3D-printed bone scaffolds and regenerative biomaterials.


7. Research & Biomedical Studies

  • Model nanomaterial for studying ion exchange, biomineralization, and biointerface interactions.

  • Useful in nanomedicine, tissue scaffolding, and biomaterials engineering research.


⚠️ Handling & Storage

  • Store in a sealed container in a cool, dry environment.

  • Avoid exposure to moisture and CO₂ to prevent surface reaction.

  • Handle with gloves, mask, and eye protection to avoid nanoparticle inhalation.

  • Sterilize before biomedical use (e.g., by autoclaving or UV exposure).